To summarize clearly:

The most iconic escape occurs in . After an entire season of planning, Michael and seven other inmates (the "Fox River Eight") finally make their move through the psychiatric ward and over the prison walls.

, Michael orchestrates a final breakout to free Sara Tancredi from the Miami-Dade State Penitentiary.

By this point, Michael’s original plan had been sabotaged repeatedly. The pipe he needed to access was replaced, the bolt for the toilet was missing, and the Psychiatric Ward access was compromised. In "Go," Michael finalizes a new, more dangerous route through the asylum.