What Is Episodic Migraine ~repack~ Online

Diagnosis is clinical. There is no blood test or MRI to confirm migraine. The "POUND" mnemonic is useful for differential diagnosis:

In , CSD is a wave of neuronal depolarization moving across the cortex at 2–6 mm/min, followed by prolonged suppression of neural activity. CSD activates the trigeminovascular system and triggers aura (visual, sensory, or speech disturbances). what is episodic migraine

| Drug Class | Examples | Evidence Level | Common Side Effects | |------------|----------|----------------|----------------------| | | Propranolol, metoprolol | High | Fatigue, cold extremities, bradycardia | | Anticonvulsants | Topiramate, valproate | High (topiramate) | Paresthesias, word-finding difficulty, weight loss (topiramate); teratogenicity | | Antidepressants | Amitriptyline, venlafaxine | Moderate | Dry mouth, sedation, weight gain | | CGRP mAbs | Erenumab, galcanezumab, fremanezumab | High | Injection site reactions; low systemic toxicity | | Gepants (oral preventive) | Atogepant, rimegepant | High | Constipation, nausea | | Botulinum toxin A | OnabotulinumtoxinA | Only for chronic migraine | Neck weakness, dysphagia (rare) | Diagnosis is clinical