Often, a blocked duct is exacerbated by inflammation or debris at the eyelid margin (blepharitis). Keeping the area sterile is crucial to prevent infection.

Some herbal preparations have anecdotal support but lack strong clinical evidence for blocked ducts specifically. They may help with associated blepharitis or conjunctivitis.

Gentle pressure increases hydrostatic pressure in the tear sac, which may pop open membranous obstructions (common in infants) or help propel viscous debris through a narrowed duct.