If you want a clean “do the brothers get caught for good?” — no. They escape repeatedly, often at great cost. But characters are caught, jailed, or killed along the way. The show’s genius is making you realize: getting caught is just the start of the next plan.
– This is where the show becomes a national cat-and-mouse. Throughout the season, most of the Fox River Eight are either killed or recaptured. By the finale, Michael Scofield is sent back to prison (a new one in Panama: Sona). So yes — he gets caught again.
Recaptured multiple times, most notably at the end of Season 2 (sent to Sona ) and again at the end of the series (returned to Fox River ).
Successfully escapes Fox River but is caught at the end of Season 2 in Panama and sent to Sona .